Research Scientist — Wang Lab (Cancer Signaling & Therapeutics)
Department of Pharmacology & Chemical Biology, University of Pittsburgh
Position Summary
The Wang Laboratory in the Department of Pharmacology and Chemical Biology at the University of Pittsburgh (https://www.pharmacology.us/Faculty/QimingJaneWang) seeks a highly motivated Research Scientist to lead innovative projects dissecting cancer signaling pathways and developing targeted therapeutics, with a particular focus on prostate cancer. The successful candidate will also contribute to related collaborative research efforts, including studies in cerebrovascular biology and stroke, and assume responsibility for overseeing daily laboratory operations and mentoring junior researchers and students.
Research Focus: Dissecting oncogenic signaling networks in prostate cancer, Preclinical evaluation of candidates in cellular and rodent cancer models, Mechanistic studies linking genotype to therapeutic response and resistance, Target discovery and validation using genome engineering and functional screens, Development of quantitative, multi-omic assays to profile pathway activity and drug effects.
Required Qualifications: PhD (or equivalent) in a relevant field (e.g., Molecular Biology, Cell Biology, Genetics, Cancer Biology, Chemical Biology), Experience with rodent models (e.g., xenograft, GEMM, orthotopic or PDX; stroke-related models), Demonstrated ability to work independently and drive projects to completion, Strong hands-on training in molecular biology, cell biology, mouse genetics, and signal transduction, Experience in bioinformatics and omics analysis (e.g., RNA-seq/single-cell RNA-seq). Strong scientific writing and communication skills and the ability to work effectively in a multidisciplinary team.
Appointment, Salary & Benefits: Full-time Research Scientist staff position with comprehensive University of Pittsburgh benefits including health, dental, and vision insurance, retirement savings plans, etc. Competitive salary commensurate with experience and qualifications. Access to University of Pittsburgh resources and collaborative research community.
Application Instructions: Please email a single PDF containing: Cover letter summarizing your research interests and career goals, CV, Contact information for 2–3 references.
Email applications or inquiries to Dr. Qiming Jane Wang: qjw1@pitt.edu
Conducts independent scientific research projects from inception to presentation. Prepares and crafts various documentations of research results into manuscripts, proposals, grant applications, and presentations. Trains undergraduates and research technicians. Manages laboratory policies and coordinates project development in collaboration with other specialists.
Computer work: walking from place to place; standing and sitting to perform essential tasks. Good manual dexterity.
Lifting and stacking of boxes of supplies, standing for extended periods required to fulfill workload. Light - Maximum lifting of up to 20 lbs. With frequent lifting/carrying of up to 10 lbs. or a negligible amount; significant walking or standing may be required or may involve sitting with a degree of pushing and pulling.
The University of Pittsburgh is an equal opportunity employer / disability / veteran.